Clinical Studies

The Journal of Clinical and Aesthetic Dermatology

86-90% Patient Satisfaction | 1-2% Instance of Minor Side Effects | 0% Major Side Effects

University of Florida

Oxford STUDY

Over 18,000 injections | Average 1.5-inch waistline reduction | Minor and Rare Side Effects
  • Over 18,000 injections.
  • 97.6% of participants had a reduction in fat deposits and skin reduction.
  • Both the injection formula and technique are standardized, resulting in no “cocktail” formulations.
  • The average response to abdominal lipodissolve is a 1.5-inch waistline reduction.
  • Smooth skin retraction without rippling, creasing, or local indentations was observed in all patients.

Lipodissolve is an innovative technique involving injections to reduce the size of localized fat deposits and promote skin retraction. Achieving successful results with Lipodissolve hinges on employing the correct formula and injection technique and ensuring that patients are suitable for the procedure.

Recent studies show that the PPC/deoxycholate formulation used in Lipodissolve can cause significant cell lysis, effectively dissolving unwanted fat cells.

The current study discussed in the article involved over 18,000 Lipodissolve injections. Post-treatment, the vast majority of these patients reported improvements in their localized fat deposits without any major complications. 

STUDY Images

Figure 1. A, Pretreatment view of a 51-year-old woman who complained of skin laxity in the epigastric region. She was injected in 2 sessions using the standard Lipodissolve formula. B, Significant improvement is shown following the first injection. C,Four weeks after the first injection session, she underwent a second treatment in the same area. She received a more superficial injection technique, resulting in a much more dramatic improvement in skin retraction.
Figure 2. A, C, E, Pretreatment views of a 32-year-old woman complaining of cellulite and saddlebags. B, D, F, Posttreatment views 6 weeks after undergoing 3 sessions of Lipodissolve injections in her outer thighs (saddlebags) and posterior thigh (cellulite). Significant improvement was noted in both areas.
Figure 3. A, Pretreatment view of a 53-year-old woman who was undergoing abdominoplasty and wished to improve her overhanging back roll. B, Post-treatment view following abdominoplasty. Fifty mL of Lipodissolve was injected bilaterally during one session. Dramatic reduction in the fat deposit was accompanied by smooth skin retraction
Figure 4. A Pretreatment view of a 52-year-old man who complained of periumbilical abdomen and flank excess despite workouts and dietary modification. B, Post-treatment view after one injection with 78 mL of Lipodissolve. Definite improvement in the laxity and overhang of the abdomen and a change in vertical measurement between the pubic fold and umbilicus can be seen.
Figure 5. A Pretreatment view of a 52-year-old man. B, Post-treatment review 6 weeks after 2 injection sessions demonstrates reduction in the flank area.
Figure 6. A, C, Pretreatment views of a 48-year-old woman. B, D, Facial injections were performed in the area of the jowls, submental chin, and submandibular jawline. Great care must be taken in treating these because the fat layer is very thin. Superficial injections precisely placed are the key to success in the face.
Figure 8. A, Pretreatment view of a 28-year-old woman who requested treatment for rippling inthe thigh area following lipoplasty; she had no real residual fat, just skin contour irregularities. B, Some improvement was seen in the treated areas after 2 sessions.
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